CM – NFL Picks Against the Spread, Week 16: Will the Colts Beat the Cardinals?


By Charles Curtis, Charles McDonald and Prince J. Grimes |

Dec. 23, 2021 8:13 p.m. ET

We are in the 16th week of the NFL, which will play against the San Francisco 49ers and the Tennessee Titans on Thursday. That means it’s time again for our weekly look at point spreads to help you win some cash.

Last week, Charles Curtis picked up 6-8 (110-111 total record), Charles McDonald 8 -6 (92-102 total) and Prince Grimes went 5-9 (22-20 total).

Prince: The Lions hit the Cardinals for screaming loudly. It was just one of those weeks. We’re moving forward.

Weird things can happen on Thursday night, but I think the Niners have found their way and will take care of business.

The 49ers look like the team we were before Expected season. I think they win big.

The Titans team we just saw against the Steelers won’t be able to do much against one of the hottest teams in the league.

I hesitated a second about that Thinking about defense of the Browns, but I don’t think they’ll have enough to stop Aaron Rodgers.

The Packers could be the best team in the NFL, even if the Browns were healthy they’d get the dice rolled in this game.

I’m looking for Aaron Rodgers to continue his MVP campaign and the Browns who do absolutely nothing about it.

I’m buying into the fighting Cardinals to save myself from losing to the … Lions … or the recovering exploding colts? It’s Indy!

Hello Jonathan Taylor! This is a perfect matchup for the best running back in the league of the year, who will face the Cardinals’ weak run defense. I think the Colts can ride him to victory.

The cards are sliding, but I still trust their oeuvre more than Indy.

I’m back to not betting against Bill Belichick at home this season . The spread is close enough to make me feel okay with this selection.

I think the Bills can cover that range and potentially win as long as the weather doesn’t get out of hand like last time. The Bills defense should be able to put a brake on Mac Jones when he has more opportunities to throw the ball.

The weather should be a little tamer than when these teams first met, meaning Mac Jones might have to do a little more. I’ll put the points in a tight.

Cam Newton, Sam Darnold … doesn’t matter. The Bucs defense will keep the Panthers from doing much.

Tampa may have to play more conservatively than usual with all the injuries, but I just can’t trust Carolina to score enough to stay competitive. </ Is this distribution tight because Austin Ekeler could miss the game? I can not explain. But that's a pretty easy choice.

Tyler Huntley was impressive in the place of Lamar Jackson. So if he plays again, maybe he’ll keep it? It’s a coin toss, but I think Joe Burrow is having a monster day trying to make it one of the home favorites.

The Ravens are just too crazy. Maybe they can keep it close, but the Bengals are way healthier at this point.

I’m torn here but I’m just going to be rolling with the healthier team at this point.

That is quite a wide range for a team that just had a victory over the Cardinals and for a squad that suddenly took off.

Lions have a chance to win, let alone cover the spread. This Falcons team is brutally bad.

What if the Giants start Jake Fromm? How can I support you? I know Philly isn’t great, and I know the Giants’ defense can be tougher than you think. But I can’t.

The Giants held Philly until their last meeting until seven. That won’t happen again, but I could see another close game.

If L.A. is who we think they are, this is a game they win AND cover. But I can’t rock the way the Vikings keep things tight.

Call it a gut instinct, but it feels like one of those weird games where the Vikings show up and win.

I’m me just not sure I can support this fighting Seahawks offensive to cover it. Quite a wide range considering how they’ve been playing lately.

Justin Fields is talented and looks like a potential star for the Bears, but they’re easy to outmatch against anyone.

Seattle doesn’t stop the pass but they were decent enough against the barrel. One-dimensional is the last thing the Bears Offensive needs to be.

Think this spread could be an overreaction to the Raiders’ performance against the Browns. This is a more normal week and you should be able to clear that line pretty easily.

I hate how big the spread is, but if the Chiefs are really back they’ll win this game by two points Head start.

The Steelers always manage to avoid terrible records, but this team is not very good. You will really have difficulty moving the ball against this enhanced Chiefs defense.

I am hesitant to make this choice because of the KC coronavirus outbreak. But when enough of their great playmakers return, I like the Chiefs covering.

Too wide a range for two division teams just clashing, with Dallas winning by just seven points.

The Cowboys- Offensive doesn’t have to be brought back to life to eradicate this spread. Washington is #not good.

At what point do we stop expecting Dallas’ offense to turn back into something it may not be?

A good setup for Taysom Hill to thrive and for the formidable Saints D to keep the dolphins from doing a lot.

The Saints defense carries this team and I think they will be able to give Tua and the Dolphins offensive some real fits .

The New Orleans Defense regained some of their form last week. Let’s see if they can hold out.

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Charles is a writer for For The Win. He once dropped a simple foul ball at Shea Stadium and was booed (and never recovered) by 35,000 angry Mets fans.

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