CM – Novavax coronavirus vaccine: when can I get it and how does it work?

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Maryland-based biotech company Novavax could launch a new coronavirus vaccine soon, about a year after Americans first rolled up their sleeves.

Below are reader questions about the vaccine as well some others put together by the Herald and / or Novavax.

When can I get a Novavax coronavirus vaccine? The vaccine called NVX-CoV2373 is not currently available in the US. The company expects to submit data to the Food and Drug Administration by the end of the year. Once approval is requested, there is a rigorous review process before the shot is released to the general public.

What makes this coronavirus vaccine different from the ones we already have? The Novavax vaccine is protein based and uses the same platform as shingles and hepatitis vaccines. The proteins deliver immune stimulation directly to a person’s cells, as opposed to a fragment of the genetic code. It’s not an mRNA like Moderna and Pfizer, or an adenovirus vector like Johnson & Johnson vax.

How does it work? The Novavax coronavirus vaccine is made from the genetic sequence of the coronavirus using nanoparticle technology. The technology binds to human receptors that are attacked by viruses, which is critical for effective protection. When the vaccine is injected, it stimulates the immune system to produce antibodies.

Is it safe and effective? Clinical studies for the Novavax syringe have shown an overall effectiveness of 90% against the coronavirus and 100% protection against moderate and severe illnesses. The most common side effects are pain and tenderness at the injection site, fatigue, headache, and muscle pain. No single side effect was reported by more than 1% of study participants.

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Can foreign travelers provide proof of Novavax vaccine to enter the United States? Yes sir. Participants in Novavax clinical trials from locations outside the US are considered fully vaccinated if they have received the same product that was given in the US clinical trials. It’s one of the vaccines already approved for air travel by the Centers for Disease Control and Prevention in the US that will pass the 30,000 in the study for the jab while other shots didn’t make the cut. p> Could children get this vaccine? The vaccine is not yet approved in the United States, but Novavax initiated a pediatric expansion of a Phase 3 clinical trial in children aged 12 to 17 years in May 2021. The company intends to pursue approval in this age group and in younger age groups.

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