World News – AU – Why Mesoblast (ASX: MSB) stock is down 11%


. .

For a limited time, The Motley Fool Australia is releasing an urgent new investment report detailing our 5 favorite stocks for investors over 50. Every company has strong growth prospects for the next 3 to 5 years and most importantly, each pays a generous (and fully stamped) dividend! So if you want to get your finances in order and are in or about to retire, you’ve come to the right place!

ASX 200 | A B C D E F G H I J L M N O P Q R S T U V W X

The Motley Fool Australia Stock Market News Why Mesoblast (ASX: MSB) Is Down 11%

James Mickleboro | 15th. December 2020, 10:18 am | More on: MSB

Mesoblast Limited (ASX: MSB) stock price came under pressure Tuesday following the release of an announcement.

At the time of writing, allogeneic cellular drug developers’ stakes have dropped 11% to $ 4. 03.

This morning, Mesoblast announced key findings from DREAM-HF’s landmark Phase 3 randomized controlled trial of its allogeneic cell therapy Rexlemestrocel-L (REVASCOR) in 537 patients with advanced chronic heart failure.

According to the press release, patients with advanced chronic heart failure who received a single endomyocardial treatment with Rexlemestrocel-L in addition to maximal therapies had a 60% reduction in the frequency of heart attacks or strokes and a 60% reduction after a 30-month follow-up period ig reduction in death from cardiac causes when treated earlier in the disease’s progression.

Despite this reduction in the default endpoint of cardiac death, there was no reduction in recurrent non-fatal decompensated heart failure events. This was the primary endpoint of the study.

Management believes that this suggests that Rexlemestrocel-L lowers mortality through mechanisms different from existing drugs that lower hospital stay rates but do not significantly affect cardiac mortality.

Dr. Silviu Itescu, Chief Executive of Mesoblast, commented: “There is an urgent need for new therapies that can reduce the high mortality rates in patients with heart failure through different mechanisms of action of existing drugs that lower hospital stay rates but have not significantly reduced death rates. ”

« The mortality reduction observed with Rexlemestrocel-L in advanced chronic heart failure underscores the power of this technology and Mesoblast’s commitment to treating diseases in patients with high unmet needs that are inadequate over existing therapies, » he added.

Although the primary endpoint may not have been met, management still sees potential for therapy.

Dr. Fred Grossman, Mesoblast’s Chief Medical Officer, stated, “We believe that the mortality benefit seen in this landmark Phase 3 study will support a potential avenue for approval of Rexlemestrocel-L in patients with advanced chronic heart failure. We plan to discuss possible avenues for approval based on mortality reduction with the US Food and Drug Administration. ”

When investment expert Scott Phillips has a stock tip, it can be worth listening. After all, the Motley Fool Share Advisor’s flagship newsletter, which it has operated for more than eight years, has offered thousands of paying members stock choices that have doubled, tripled, or even more. *

Scott just revealed what he thinks are the top five ASX stocks investors can buy right now. These stocks trade at dirt cheap prices, and Scott thinks they are great buys right now.

James Mickleboro, a contributor to the Motley Fool, has no position in any of the stocks mentioned. The Motley Fool Australia has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). . Authorized by Bruce Jackson.

In this FREE SHARE REPORT, Scott Phillips just revealed what he thinks are the 3 ASX stocks for the post-COVID world that investors should buy now while they still can.

. Fools Ecap. Fool-ecap-id-19. Fool-Ecap-Type-Vanilla {background: # fff7c4;} aside section . Fool-ecap-id-19. Fool-ecap-type-vanilla h3 {font size: 1. 6em;} p. ecap disclaimer {font size: 0. 6em! Important;} div. Fools Ecap. Narr-Ecap-ID-19-Form {position: relative; Text alignment: center; Edge: . 2em 1em;}. Fools Ecap. Fool-Ecap-ID-19 p. ecap disclaimer {margin-left: 0px;} . Fools Ecap. Fool-Ecap-ID-19 p. via email {bottom margin: 0px; Text alignment: middle;} div. Fools Ecap. Narr-Ecap-ID-19 p {color: # 464646;}. Fools Ecap Type Vanilla. Narr-Ecap-ID-19 h3 {color: # 404040; Advertisement: Block! important;}. Fools Ecap Type Vanilla. Fool-ecap-id-19 . ecap disclaimer {color: # 484848! important;}. Fool-ecap-id-19. Fool Ecap Type Vanilla h3. Title {display: none! important;} . Fools Ecap. Fool-ecap-id-19. Fool-ecap-type-vanilla {bottom-edge: 10px;}. Fools Ecap Type Vanilla. Narr-Ecap-ID-19 input [type = « send »] {margin: . 5rem 0 . 5rem! Important;}. Fools Ecap. fool-ecap-id-19 img {display: inline;}

By clicking this button you agree to our terms of use and privacy policy. We only use your email address to keep you informed about updates to our website and about other products and services that we think may interest you. You can unsubscribe at any time. Further information can be found in our Financial Services Guide (FSG).

This service only provides general, not personalized, financial advice and has not taken your personal circumstances into account. The Motley Fool Australia operates under AFSL 400691. You can find more information in our Financial Services Guide. Please remember that investments can go up and down. Past performance is not necessarily an indication of future returns. The Motley Fool Australia does not guarantee any performance or return on any investment.

Mesoblast, Heart Failure, ASX: MSB, Cell Therapy, ASX, Myocardial Infarction

World News – AU – Why Mesoblast (ASX: MSB) ‘s share price is down 11%


Donnez votre avis et abonnez-vous pour plus d’infos

Vidéo du jour: